Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice

The neurotoxicity of paraquat dichloride (PQ) was assessed in two inbred strains of 9- or 16-week old male C57BL/6 mice housed in two different laboratories and compared to the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). PQ was administered by intraperitoneal injections; either o...

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Detalles Bibliográficos
Autores principales: Smeyne, Richard Jay, Breckenridge, Charles B., Beck, Melissa, Jiao, Yun, Butt, Mark T., Wolf, Jeffrey C., Zadory, Dan, Minnema, Daniel J., Sturgess, Nicholas C., Travis, Kim Z., Cook, Andrew R., Smith, Lewis L., Botham, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082881/
https://www.ncbi.nlm.nih.gov/pubmed/27788145
http://dx.doi.org/10.1371/journal.pone.0164094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082881/
https://www.ncbi.nlm.nih.gov/pubmed/27788145
http://dx.doi.org/10.1371/journal.pone.0164094

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