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Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice
In female mammals, activation of Xist (X-inactive specific transcript) is essential for establishment of X chromosome inactivation. During early embryonic development in mice, paternal Xist is preferentially expressed whereas maternal Xist (Xm-Xist) is silenced. Unlike autosomal imprinted genes, Xis...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082930/ https://www.ncbi.nlm.nih.gov/pubmed/27788132 http://dx.doi.org/10.1371/journal.pgen.1006375 |