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Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions

Despite sustained biomedical research effort, influenza A virus remains an imminent threat to the world population and a major healthcare burden. The challenge in developing vaccines against influenza is the ability of the virus to mutate rapidly in response to selective immune pressure. Hemagglutin...

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Detalles Bibliográficos
Autores principales: Khatri, Kshitij, Klein, Joshua A., White, Mitchell R., Grant, Oliver C., Leymarie, Nancy, Woods, Robert J., Hartshorn, Kevan L., Zaia, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083086/
https://www.ncbi.nlm.nih.gov/pubmed/26984886
http://dx.doi.org/10.1074/mcp.M116.058016