Cargando…

Quantitative Tagless Copurification: A Method to Validate and Identify Protein-Protein Interactions

Identifying protein-protein interactions (PPIs) at an acceptable false discovery rate (FDR) is challenging. Previously we identified several hundred PPIs from affinity purification - mass spectrometry (AP-MS) data for the bacteria Escherichia coli and Desulfovibrio vulgaris. These two interactomes h...

Descripción completa

Detalles Bibliográficos
Autores principales: Shatsky, Maxim, Dong, Ming, Liu, Haichuan, Yang, Lee Lisheng, Choi, Megan, Singer, Mary E., Geller, Jil T., Fisher, Susan J., Hall, Steven C., Hazen, Terry C., Brenner, Steven E., Butland, Gareth, Jin, Jian, Witkowska, H. Ewa, Chandonia, John-Marc, Biggin, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083090/
https://www.ncbi.nlm.nih.gov/pubmed/27099342
http://dx.doi.org/10.1074/mcp.M115.057117