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Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures

Adjuvants boost vaccine responses, enhancing protective immunity against infections that are most common among the very young. Many adjuvants activate innate immunity, some via Toll-Like Receptors (TLRs), whose activities varies with age. Accordingly, characterization of age-specific adjuvant-induce...

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Detalles Bibliográficos
Autores principales: Oh, Djin-Ye, Dowling, David J., Ahmed, Saima, Choi, Hyungwon, Brightman, Spencer, Bergelson, Ilana, Berger, Sebastian T., Sauld, John F., Pettengill, Matthew, Kho, Alvin T., Pollack, Henry J., Steen, Hanno, Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083103/
https://www.ncbi.nlm.nih.gov/pubmed/26933193
http://dx.doi.org/10.1074/mcp.M115.055541