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MeCP2 and Histone Deacetylases 1 and 2 in Dorsal Striatum Collectively Suppress Repetitive Behaviors
Class I histone deacetylases (HDACs), HDAC1 and HDAC2 often associate together in protein complexes with transcriptional factors such as methyl-CpG-binding protein 2 (MeCP2). Given their high degree of sequence identity, we examined the functional redundancy of HDAC1 and HDAC2 in mature brain. We de...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083208/ https://www.ncbi.nlm.nih.gov/pubmed/27668390 http://dx.doi.org/10.1038/nn.4395 |