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Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

Microglia activation is a neuroinflammatory response to parenchymal damage with release of intracellular metabolites, e.g., purines, and signaling molecules from damaged cells. Extracellular purines can elicit Ca(2+)-mediated microglia activation involving P2X/P2Y receptors with metabotropic (P2Y) a...

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Detalles Bibliográficos
Autores principales: Gilbert, Daniel F., Stebbing, Martin J., Kuenzel, Katharina, Murphy, Robyn M., Zacharewicz, Evelyn, Buttgereit, Andreas, Stokes, Leanne, Adams, David J., Friedrich, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083710/
https://www.ncbi.nlm.nih.gov/pubmed/27840602
http://dx.doi.org/10.3389/fnmol.2016.00111