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Antioxidant and anti-inflammatory action of melatonin in an experimental model of secondary biliary cirrhosis induced by bile duct ligation

AIM: To evaluate the effects of melatonin (Mel) on oxidative stress in an experimental model of bile duct ligation (BDL). METHODS: Male Wistar rats (n = 32, weight ± 300 g) were allocated across four groups: CO (sham BDL), BDL (BDL surgery), CO + Mel (sham BDL and Mel administration) and BDL + Mel (...

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Detalles Bibliográficos
Autores principales: Colares, Josieli Raskopf, Schemitt, Elizângela Gonçalves, Hartmann, Renata Minuzzo, Licks, Francielli, Soares, Mariana do Couto, Bosco, Adriane Dal, Marroni, Norma Possa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083797/
https://www.ncbi.nlm.nih.gov/pubmed/27833383
http://dx.doi.org/10.3748/wjg.v22.i40.8918