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Presence of a Prophage Determines Temperature-Dependent Capsule Production in Streptococcus pyogenes

A hyaluronic acid capsule is a major virulence factor in the pathogenesis of Streptococcus pyogenes. It acts as an anti-phagocytic agent and adhesin to keratinocytes. The expression of the capsule is primarily regulated at the transcriptional level by the two-component regulatory system CovRS, in wh...

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Detalles Bibliográficos
Autores principales: Brown, Leslie, Kim, Jeong-Ho, Cho, Kyu Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083913/
https://www.ncbi.nlm.nih.gov/pubmed/27669311
http://dx.doi.org/10.3390/genes7100074