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Presence of a Prophage Determines Temperature-Dependent Capsule Production in Streptococcus pyogenes
A hyaluronic acid capsule is a major virulence factor in the pathogenesis of Streptococcus pyogenes. It acts as an anti-phagocytic agent and adhesin to keratinocytes. The expression of the capsule is primarily regulated at the transcriptional level by the two-component regulatory system CovRS, in wh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083913/ https://www.ncbi.nlm.nih.gov/pubmed/27669311 http://dx.doi.org/10.3390/genes7100074 |