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Presence of a Prophage Determines Temperature-Dependent Capsule Production in Streptococcus pyogenes

A hyaluronic acid capsule is a major virulence factor in the pathogenesis of Streptococcus pyogenes. It acts as an anti-phagocytic agent and adhesin to keratinocytes. The expression of the capsule is primarily regulated at the transcriptional level by the two-component regulatory system CovRS, in wh...

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Detalles Bibliográficos
Autores principales:	Brown, Leslie, Kim, Jeong-Ho, Cho, Kyu Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083913/ https://www.ncbi.nlm.nih.gov/pubmed/27669311 http://dx.doi.org/10.3390/genes7100074

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