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YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine

Resveratrol, a natural polyphenol present in most plants, inhibits the growth of numerous cancers both in vitro and in vivo. Aberrant expression of YAP has been reported to activate multiple growth-regulatory pathways and confer anti-apoptotic abilities to many cancer cells. However, the role of res...

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Detalles Bibliográficos
Autores principales: Jiang, Zhengdong, Chen, Xin, Chen, Ke, Sun, Liankang, Gao, Luping, Zhou, Cancan, Lei, Meng, Duan, Wanxing, Wang, Zheng, Ma, Qingyong, Ma, Jiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083973/
https://www.ncbi.nlm.nih.gov/pubmed/27669292
http://dx.doi.org/10.3390/nu8100546