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Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes

Renal tubular injury is a critical factor in the pathogenesis of diabetic nephropathy (DN). Endoplasmic reticulum (ER) stress is involved in diabetic nephropathy. Tauroursodeoxycholic acid (TUDCA) is an effective inhibitor of ER stress. Here, we investigated the role of TUDCA in the progression of t...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Fan, Ying, Zeng, Chuchu, He, Li, Wang, Niansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083977/
https://www.ncbi.nlm.nih.gov/pubmed/27669287
http://dx.doi.org/10.3390/nu8100589