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DNA sensor cGAS-mediated immune recognition

The host takes use of pattern recognition receptors (PRRs) to defend against pathogen invasion or cellular damage. Among microorganism-associated molecular patterns detected by host PRRs, nucleic acids derived from bacteria or viruses are tightly supervised, providing a fundamental mechanism of host...

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Detalles Bibliográficos
Autores principales: Xia, Pengyan, Wang, Shuo, Gao, Pu, Gao, Guangxia, Fan, Zusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084157/
https://www.ncbi.nlm.nih.gov/pubmed/27696330
http://dx.doi.org/10.1007/s13238-016-0320-3