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ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair

Faithful DNA repair is essential to maintain genome integrity. Ultraviolet (UV) irradiation elicits both the recruitment of DNA repair factors and the deposition of histone marks such as monoubiquitylation of histone H2A at lesion sites. Here, we report how a ubiquitin E3 ligase complex specific to...

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Detalles Bibliográficos
Autores principales: Gracheva, Ekaterina, Chitale, Shalaka, Wilhelm, Thomas, Rapp, Alexander, Byrne, Jonathan, Stadler, Jens, Medina, Rebeca, Cardoso, M. Cristina, Richly, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084270/
https://www.ncbi.nlm.nih.gov/pubmed/27091446
http://dx.doi.org/10.1083/jcb.201506099