PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

Mitochondrial fission is essential for the degradation of damaged mitochondria. It is currently unknown how the dynamin-related protein 1 (DRP1)–associated fission machinery is selectively targeted to segregate damaged mitochondria. We show that PTEN-induced putative kinase (PINK1) serves as a pro-f...

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Detalles Bibliográficos
Autores principales: Pryde, Kenneth R., Smith, Heather L., Chau, Kai-Yin, Schapira, Anthony H.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084273/
https://www.ncbi.nlm.nih.gov/pubmed/27091447
http://dx.doi.org/10.1083/jcb.201509003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084273/
https://www.ncbi.nlm.nih.gov/pubmed/27091447
http://dx.doi.org/10.1083/jcb.201509003

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