Cargando…
Application of RNAi-induced gene expression profiles for prognostic prediction in breast cancer
Homologous recombination (HR) is the primary pathway for repairing double-strand DNA breaks implicating in the development of cancer. RNAi-based knockdowns of BRCA1 and RAD51 in this pathway have been performed to investigate the resulting transcriptomic profiles. Here we propose a computational fra...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084341/ https://www.ncbi.nlm.nih.gov/pubmed/27788678 http://dx.doi.org/10.1186/s13073-016-0363-3 |