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Application of RNAi-induced gene expression profiles for prognostic prediction in breast cancer

Homologous recombination (HR) is the primary pathway for repairing double-strand DNA breaks implicating in the development of cancer. RNAi-based knockdowns of BRCA1 and RAD51 in this pathway have been performed to investigate the resulting transcriptomic profiles. Here we propose a computational fra...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Mark, Kenneth M. K., Ung, Matthew H., Kettenbach, Arminja, Miller, Todd, Xu, Wei, Cheng, Wenqing, Xia, Tian, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084341/
https://www.ncbi.nlm.nih.gov/pubmed/27788678
http://dx.doi.org/10.1186/s13073-016-0363-3