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Specific disruption of Lnk in murine endothelial progenitor cells promotes dermal wound healing via enhanced vasculogenesis, activation of myofibroblasts, and suppression of inflammatory cell recruitment

BACKGROUND: Although endothelial progenitor cells (EPCs) contribute to wound repair by promoting neovascularization, the mechanism of EPC-mediated wound healing remains poorly understood due to the lack of pivotal molecular targets of dermal wound repair. METHODS AND RESULTS: We found that genetic t...

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Detalles Bibliográficos
Autores principales: Lee, Jun Hee, Ji, Seung Taek, Kim, Jaeho, Takaki, Satoshi, Asahara, Takayuki, Hong, Young-Joon, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084514/
https://www.ncbi.nlm.nih.gov/pubmed/27793180
http://dx.doi.org/10.1186/s13287-016-0403-3