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Costimulation Blockade in Kidney Transplantation: An Update

In the setting of solid-organ transplantation, calcineurin inhibitor (CNI)-based therapy remains the cornerstone of immunosuppression. However, long-term use of CNIs is associated with some degree of nephrotoxicity. This has led to exploring the blockade of some costimulation pathways as an efficien...

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Detalles Bibliográficos
Autores principales: Malvezzi, Paolo, Jouve, Thomas, Rostaing, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084636/
https://www.ncbi.nlm.nih.gov/pubmed/27472094
http://dx.doi.org/10.1097/TP.0000000000001344