The ubiquitin ligase CRL2(ZYG11) targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage

The anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase is known to target the degradation of cyclin B1, which is crucial for mitotic progression in animal cells. In this study, we show that the ubiquitin ligase CRL2(ZYG-11) redundantly targets the degradation of cyclin B1 in Caenorhabditi...

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Detalles Bibliográficos
Autores principales: Balachandran, Riju S., Heighington, Cassandra S., Starostina, Natalia G., Anderson, James W., Owen, David L., Vasudevan, Srividya, Kipreos, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084644/
https://www.ncbi.nlm.nih.gov/pubmed/27810909
http://dx.doi.org/10.1083/jcb.201601083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084644/
https://www.ncbi.nlm.nih.gov/pubmed/27810909
http://dx.doi.org/10.1083/jcb.201601083

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