FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors

FBXW7 is a ubiquitin ligase that mediates ubiquitylation of oncoproteins, such as c‐Myc, cyclin E, Notch and c‐Jun. FBXW7 is a known tumor‐suppressor gene, and mutations in FBXW7 have been reported in various human malignancies. In this study, we examined the sequences of the FBXW7 and p53 genes in...

Descripción completa

Detalles Bibliográficos
Autores principales: Kitade, Shoko, Onoyama, Ichiro, Kobayashi, Hiroaki, Yagi, Hiroshi, Yoshida, Sachiko, Kato, Masaya, Tsunematsu, Ryosuke, Asanoma, Kazuo, Sonoda, Kenzo, Wake, Norio, Hata, Kenichiro, Nakayama, Keiichi I., Kato, Kiyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084658/
https://www.ncbi.nlm.nih.gov/pubmed/27486687
http://dx.doi.org/10.1111/cas.13026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084658/
https://www.ncbi.nlm.nih.gov/pubmed/27486687
http://dx.doi.org/10.1111/cas.13026

Ejemplares similares