Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer–stromal interactions in a mouse xenograft model

Desmoplasia contributes to the aggressive behavior of pancreatic cancer. However, recent clinical trials testing several antifibrotic agents on pancreatic cancer have not shown clear efficacy. Therefore, further investigation of desmoplasia‐targeting antifibrotic agents by another mechanism is neede...

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Detalles Bibliográficos
Autores principales: Yoshida, Masaki, Miyasaka, Yoshihiro, Ohuchida, Kenoki, Okumura, Takashi, Zheng, Biao, Torata, Nobuhiro, Fujita, Hayato, Nabae, Toshinaga, Manabe, Tatsuya, Shimamoto, Masaya, Ohtsuka, Takao, Mizumoto, Kazuhiro, Nakamura, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084662/
https://www.ncbi.nlm.nih.gov/pubmed/27487486
http://dx.doi.org/10.1111/cas.13024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084662/
https://www.ncbi.nlm.nih.gov/pubmed/27487486
http://dx.doi.org/10.1111/cas.13024

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