Peperomin E reactivates silenced tumor suppressor genes in lung cancer cells by inhibition of DNA methyltransferase

Advanced lung cancer has poor prognosis owing to its low sensitivity to current chemotherapy agents. Therefore, discovery of new therapeutic agents is urgently needed. In this study, we investigated the antitumor effects of peperomin E, a secolignan isolated from Peperomia dindygulensis, a frequentl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xin‐zhi, Cheng, Ying, Wang, Kui‐long, Liu, Rui, Yang, Xiao‐lin, Wen, Hong‐mei, Chai, Chuan, Liang, Jing‐yu, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084666/
https://www.ncbi.nlm.nih.gov/pubmed/27501331
http://dx.doi.org/10.1111/cas.13029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084666/
https://www.ncbi.nlm.nih.gov/pubmed/27501331
http://dx.doi.org/10.1111/cas.13029

Ejemplares similares