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HP1 regulates the localization of FANCJ at sites of DNA double‐strand breaks

The breast and ovarian cancer predisposition protein BRCA1 forms three mutually exclusive complexes with Fanconi anemia group J protein (FANCJ, also called BACH1 or BRIP1), CtIP, and Abraxas/RAP80 through its BRCA1 C terminus (BRCT) domains, while its RING domain binds to BRCA1‐associated RING domai...

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Detalles Bibliográficos
Autores principales: Wu, Wenwen, Togashi, Yukiko, Johmura, Yoshikazu, Miyoshi, Yasuo, Nobuoka, Sachihiko, Nakanishi, Makoto, Ohta, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084677/
https://www.ncbi.nlm.nih.gov/pubmed/27399284
http://dx.doi.org/10.1111/cas.13008