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Continued Elevation of Interleukin-18 and Interferon-γ After Initiation of Antiretroviral Therapy and Clinical Failure in a Diverse Multicountry Human Immunodeficiency Virus Cohort

Background. We assessed immune activation after antiretroviral therapy (ART) initiation to understand clinical failure in diverse settings. Methods. We performed a case-control study in ACTG Prospective Evaluation of Antiretrovirals in Resource-Limited Settings (PEARLS). Cases were defined as incide...

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Detalles Bibliográficos
Autores principales: Balagopal, Ashwin, Gupte, Nikhil, Shivakoti, Rupak, Cox, Andrea L., Yang, Wei-Teng, Berendes, Sima, Mwelase, Noluthando, Kanyama, Cecilia, Pillay, Sandy, Samaneka, Wadzanai, Santos, Breno, Poongulali, Selvamuthu, Tripathy, Srikanth, Riviere, Cynthia, Lama, Javier R., Cardoso, Sandra W., Sugandhavesa, Patcharaphan, Semba, Richard D., Hakim, James, Hosseinipour, Mina C., Kumarasamy, Nagalingeswaran, Sanne, Ian, Asmuth, David, Campbell, Thomas, Bollinger, Robert C., Gupta, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084713/
https://www.ncbi.nlm.nih.gov/pubmed/27800521
http://dx.doi.org/10.1093/ofid/ofw118