Exclusive transmission of the embryonic stem cell‐derived genome through the mouse germline

Gene targeting in embryonic stem (ES) cells remains best practice for introducing complex mutations into the mouse germline. One aspect in this multistep process that has not been streamlined with regard to the logistics and ethics of mouse breeding is the efficiency of germline transmission: the tr...

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Detalles Bibliográficos
Autores principales: Koentgen, Frank, Lin, Jiangwei, Katidou, Markella, Chang, Isabelle, Khan, Mona, Watts, Jacqui, Mombaerts, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084746/
https://www.ncbi.nlm.nih.gov/pubmed/27012318
http://dx.doi.org/10.1002/dvg.22938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084746/
https://www.ncbi.nlm.nih.gov/pubmed/27012318
http://dx.doi.org/10.1002/dvg.22938

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