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DNA Origami Seesaws as Comparative Binding Assay

The application of commonly used force spectroscopy in biological systems is often limited by the need for an invasive tether connecting the molecules of interest to a bead or cantilever tip. Here we present a DNA origami‐based prototype in a comparative binding assay. It has the advantage of in sit...

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Detalles Bibliográficos
Autores principales: Nickels, Philipp C., Høiberg, Hans C., Simmel, Stephanie S., Holzmeister, Phil, Tinnefeld, Philip, Liedl, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084756/
https://www.ncbi.nlm.nih.gov/pubmed/27038073
http://dx.doi.org/10.1002/cbic.201600059