Cargando…

Revisiting Kadenbach: Electron flux rate through cytochrome c‐oxidase determines the ATP‐inhibitory effect and subsequent production of ROS

Mitochondrial respiration is the predominant source of ATP. Excessive rates of electron transport cause a higher production of harmful reactive oxygen species (ROS). There are two regulatory mechanisms known. The first, according to Mitchel, is dependent on the mitochondrial membrane potential that...

Descripción completa

Detalles Bibliográficos
Autores principales: Vogt, Sebastian, Rhiel, Annika, Weber, Petra, Ramzan, Rabia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084804/
https://www.ncbi.nlm.nih.gov/pubmed/27171124
http://dx.doi.org/10.1002/bies.201600043