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Effects of glucose and insulin on secretion of amyloid‐β by human adipose tissue cells
OBJECTIVE: Obesity and type 2 diabetes mellitus are risk factors for developing Alzheimer disease. Overlapping patterns of metabolic dysfunction may be common molecular links between these complex diseases. Amyloid‐β (Aβ) precursor protein and associated β‐ and γ‐secretases are expressed in adipose...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084817/ https://www.ncbi.nlm.nih.gov/pubmed/27172814 http://dx.doi.org/10.1002/oby.21494 |