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Effects of glucose and insulin on secretion of amyloid‐β by human adipose tissue cells

OBJECTIVE: Obesity and type 2 diabetes mellitus are risk factors for developing Alzheimer disease. Overlapping patterns of metabolic dysfunction may be common molecular links between these complex diseases. Amyloid‐β (Aβ) precursor protein and associated β‐ and γ‐secretases are expressed in adipose...

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Detalles Bibliográficos
Autores principales:	Tharp, William G., Gupta, Dhananjay, Smith, Joshua, Jones, Karen P., Jones, Amanda M., Pratley, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084817/ https://www.ncbi.nlm.nih.gov/pubmed/27172814 http://dx.doi.org/10.1002/oby.21494

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