Enhanced killing of chordoma cells by antibody-dependent cell-mediated cytotoxicity employing the novel anti-PD-L1 antibody avelumab

Chordoma, a rare bone tumor derived from the notochord, has been shown to be resistant to conventional therapies. Checkpoint inhibition has shown great promise in immune-mediated therapy of diverse cancers. The anti-PD-L1 mAb avelumab is unique among checkpoint inhibitors in that it is a fully human...

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Detalles Bibliográficos
Autores principales: Fujii, Rika, Friedman, Eitan R., Richards, Jacob, Tsang, Kwong Y., Heery, Christopher R., Schlom, Jeffrey, Hodge, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085098/
https://www.ncbi.nlm.nih.gov/pubmed/27172898
http://dx.doi.org/10.18632/oncotarget.9256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085098/
https://www.ncbi.nlm.nih.gov/pubmed/27172898
http://dx.doi.org/10.18632/oncotarget.9256

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