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Vaccine efficacy and T helper cell differentiation change with aging

Influenza and pneumonia are leading causes of death in elderly populations. With age, there is an increased inflammatory response and slower viral clearance during influenza infection which increases the risk of extended illness and mortality. Here we employ a preclinical murine model of influenza i...

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Detalles Bibliográficos
Autores principales: Lefebvre, Julie S., Lorenzo, Erica C., Masters, April R., Hopkins, Jacob W., Eaton, Sheri M., Smiley, Stephen T., Haynes, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085104/
https://www.ncbi.nlm.nih.gov/pubmed/27177221
http://dx.doi.org/10.18632/oncotarget.9254