An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

The aim of this study was to elucidate the molecular signature of Alzheimer's disease-associated amyloid pathology. We used the double APP(swe)/PS1(ΔE9) mouse, a widely used model of cerebral amyloidosis, to compare changes in proteome, including global phosphorylation and sialylated N-linked g...

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Detalles Bibliográficos
Autores principales: Kempf, Stefan J., Metaxas, Athanasios, Ibáñez-Vea, María, Darvesh, Sultan, Finsen, Bente, Larsen, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085108/
https://www.ncbi.nlm.nih.gov/pubmed/27144524
http://dx.doi.org/10.18632/oncotarget.9092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085108/
https://www.ncbi.nlm.nih.gov/pubmed/27144524
http://dx.doi.org/10.18632/oncotarget.9092

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