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Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia

Metabolic reprogramming is a hallmark of cancer. Understanding cancer metabolism is instrumental to devise innovative therapeutic approaches. Anabolic metabolism, including the induction of lipogenic enzymes, is a key feature of proliferating cells. Here, we report a novel tumor suppressive function...

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Detalles Bibliográficos
Autores principales: Al-Zoughbi, Wael, Pichler, Martin, Gorkiewicz, Gregor, Guertl-Lackner, Barbara, Haybaeck, Johannes, Jahn, Stephan W., Lackner, Carolin, Liegl-Atzwanger, Bernadette, Popper, Helmut, Schauer, Silvia, Nusshold, Elisa, Kindt, Alida S. D., Trajanoski, Zlatko, Speicher, Michael R., Haemmerle, Guenther, Zimmermann, Robert, Zechner, Rudolf, Vesely, Paul W., Hoefler, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085122/
https://www.ncbi.nlm.nih.gov/pubmed/27213586
http://dx.doi.org/10.18632/oncotarget.9418