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Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis

In this study, the bleomycin model of pulmonary fibrosis was utilized to investigate putative anti-fibrotic activity of Ac-SDKP in vivo. Male CD-1 mice received intra-tracheal bleomycin (BLEO, 1 mg/kg) instillation in the absence or presence of Ac-SDKP (a dose of 0.6 mg/kg delivered intra-peritoneal...

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Detalles Bibliográficos
Autores principales: Conte, Enrico, Fagone, Evelina, Gili, Elisa, Fruciano, Mary, Iemmolo, Maria, Pistorio, Maria Provvidenza, Impellizzeri, Daniela, Cordaro, Marika, Cuzzocrea, Salvatore, Vancheri, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085123/
https://www.ncbi.nlm.nih.gov/pubmed/27029074
http://dx.doi.org/10.18632/oncotarget.8409