Ergosterol peroxide activates Foxo3-mediated cell death signaling by inhibiting AKT and c-Myc in human hepatocellular carcinoma cells

Sterols are the important active ingredients of fungal secondary metabolites to induce death of tumor cells. In our previous study, we found that ergosterol peroxide (5α, 8α-epidioxiergosta-6, 22-dien-3β-ol), purified from Ganoderma lucidum, induced human cancer cell death. Since the amount of purif...

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Detalles Bibliográficos
Autores principales: Li, Xiangmin, Wu, Qingping, Bu, Ming, Hu, Liming, Du, William W., Jiao, Chunwei, Pan, Honghui, Sdiri, Mouna, Wu, Nan, Xie, Yizhen, Yang, Burton B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085130/
https://www.ncbi.nlm.nih.gov/pubmed/27058618
http://dx.doi.org/10.18632/oncotarget.8608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085130/
https://www.ncbi.nlm.nih.gov/pubmed/27058618
http://dx.doi.org/10.18632/oncotarget.8608

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