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Direct repression of the oncogene CDK4 by the tumor suppressor miR-486-5p in non-small cell lung cancer

MicroRNAs are a class of non-coding single-stranded RNA, 20-23 nucleotide in length, which can be involved in the regulation of gene expression. Through binding with 3′-untranslated regions (3′-UTR), microRNAs can cause degradation of target mRNAs or inhibition of translation, and thus regulating th...

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Detalles Bibliográficos
Autores principales: Shao, Yang, Shen, Yu-Qing, Li, Yan-Li, Liang, Chen, Zhang, Bing-Jie, Lu, Sheng-Di, He, Yan-Yun, Wang, Ping, Sun, Qiang-Ling, Jin, You-Xin, Ma, Zhong-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085134/
https://www.ncbi.nlm.nih.gov/pubmed/27049724
http://dx.doi.org/10.18632/oncotarget.8514