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Direct repression of the oncogene CDK4 by the tumor suppressor miR-486-5p in non-small cell lung cancer
MicroRNAs are a class of non-coding single-stranded RNA, 20-23 nucleotide in length, which can be involved in the regulation of gene expression. Through binding with 3′-untranslated regions (3′-UTR), microRNAs can cause degradation of target mRNAs or inhibition of translation, and thus regulating th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085134/ https://www.ncbi.nlm.nih.gov/pubmed/27049724 http://dx.doi.org/10.18632/oncotarget.8514 |