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Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100)

Although the precursor protein of NFκB2 (p100) is thought to act as a tumor suppressor in mammalian cells, the molecular mechanism of its anti-tumor activity is far from clear. Here, we are, for the first time, to report that p100 protein expression was dramatically decreased in bladder cancers of N...

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Detalles Bibliográficos
Autores principales: Xu, Jiawei, Wang, Yulei, Hua, Xiaohui, Xu, Jiheng, Tian, Zhongxian, Jin, Honglei, Li, Jingxia, Wu, Xue-Ru, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085141/
https://www.ncbi.nlm.nih.gov/pubmed/27095572
http://dx.doi.org/10.18632/oncotarget.8746