Blockade of PD-1 Signaling Enhances Th2 Cell Responses and Aggravates Liver Immunopathology in Mice with Schistosomiasis japonica

BACKGROUND: More than 220 million people worldwide are chronically infected with schistosomes, causing severe disease or even death. The major pathological damage occurring in schistosomiasis is attributable to the granulomatous inflammatory response and liver fibrosis induced by schistosome eggs. T...

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Detalles Bibliográficos
Autores principales: Zhou, Sha, Jin, Xin, Li, Yalin, Li, Wei, Chen, Xiaojun, Xu, Lei, Zhu, Jifeng, Xu, Zhipeng, Zhang, Yang, Liu, Feng, Su, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085144/
https://www.ncbi.nlm.nih.gov/pubmed/27792733
http://dx.doi.org/10.1371/journal.pntd.0005094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085144/
https://www.ncbi.nlm.nih.gov/pubmed/27792733
http://dx.doi.org/10.1371/journal.pntd.0005094

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