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XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis
Neuroblastoma is an aggressive, relapse-prone childhood tumor of the sympathetic nervous system. Current treatment modalities do not fully exploit the genetic basis between the different molecular subtypes and little is known about the targets discovered in recent mutational and genetic studies. Neu...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085151/ https://www.ncbi.nlm.nih.gov/pubmed/27097110 http://dx.doi.org/10.18632/oncotarget.8748 |