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XAF1 promotes neuroblastoma tumor suppression and is required for KIF1Bβ-mediated apoptosis

Neuroblastoma is an aggressive, relapse-prone childhood tumor of the sympathetic nervous system. Current treatment modalities do not fully exploit the genetic basis between the different molecular subtypes and little is known about the targets discovered in recent mutational and genetic studies. Neu...

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Detalles Bibliográficos
Autores principales: Choo, Zhang'e, Lin Koh, Rachel Yu, Wallis, Karin, Wei Koh, Timothy Jia, Kuick, Chik Hong, Sobrado, Veronica, Kenchappa, Rajappa S., Pheng Loh, Amos Hong, Soh, Shui Yen, Schlisio, Susanne, En Chang, Kenneth Tou, Chen, Zhi Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085151/
https://www.ncbi.nlm.nih.gov/pubmed/27097110
http://dx.doi.org/10.18632/oncotarget.8748