Genetic alterations and protein expression in combined small cell lung cancers and small cell lung cancers arising from lung adenocarcinomas after therapy with tyrosine kinase inhibitors

There are 2 hypotheses regarding the mechanism underlying the adenocarcinoma (AD) to small cell lung cancer (SCLC) transition in patients receiving Tyrosine kinase inhibitor (TKI) therapy: 1) AD gives rise to SCLC owing to the pressure of the TKI therapy, and 2) the SCLC coexists with the AD de novo...

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Detalles Bibliográficos
Autores principales: Shi, Xiaohua, Duan, Huanli, Liu, Xuguang, Zhou, Liangrui, Liang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085152/
https://www.ncbi.nlm.nih.gov/pubmed/27145273
http://dx.doi.org/10.18632/oncotarget.9083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085152/
https://www.ncbi.nlm.nih.gov/pubmed/27145273
http://dx.doi.org/10.18632/oncotarget.9083

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