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Identification of miR-34a-target interactions by a combined network based and experimental approach

Circulating miRNAs have been associated with numerous human diseases. The lack of understanding the functional roles of blood-born miRNAs limits, however, largely their value as disease marker. In a systems biology analysis we identified miR-34a as strongly associated with pathogenesis. Genome-wide...

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Detalles Bibliográficos
Autores principales: Hart, Martin, Rheinheimer, Stefanie, Leidinger, Petra, Backes, Christina, Menegatti, Jennifer, Fehlmann, Tobias, Grässer, Friedrich, Keller, Andreas, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085156/
https://www.ncbi.nlm.nih.gov/pubmed/27144431
http://dx.doi.org/10.18632/oncotarget.9103