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FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms

FRA1 (Fos-like antigen 1) is highly expressed in many epithelial cancers including squamous cell carcinoma of the skin (cSCC) and head and neck (HNSCC). However, the functional importance and the mechanisms mediating FRA1 function in these cancers are not fully understood. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoling, Wu, Joseph, Luo, Suju, Lechler, Terry, Zhang, Jennifer Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085162/
https://www.ncbi.nlm.nih.gov/pubmed/27144339
http://dx.doi.org/10.18632/oncotarget.9110