A functional variant at miRNA-122 binding site in IL-1α 3′ UTR predicts risk of recurrence in patients with oropharyngeal cancer

IL-1α, an important regulator of immune and inflammation responses, has been implicated in cancer development and prognosis. An insertion (Ins)/deletion (Del) polymorphism (IL-1α rs3783553) in the 3′ UTR of IL-1α may disrupt a binding site for miRNA-122 and may affect its transcription level. Thus,...

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Detalles Bibliográficos
Autores principales: Wang, Chengyuan, Sturgis, Erich M., Chen, Xingming, Wei, Qingyi, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085169/
https://www.ncbi.nlm.nih.gov/pubmed/27121322
http://dx.doi.org/10.18632/oncotarget.8908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085169/
https://www.ncbi.nlm.nih.gov/pubmed/27121322
http://dx.doi.org/10.18632/oncotarget.8908

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