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MnTnBuOE-2-PyP protects normal colorectal fibroblasts from radiation damage and simultaneously enhances radio/chemotherapeutic killing of colorectal cancer cells

Manganese porphyrins have been shown to be potent radioprotectors in a variety of cancer models. However, the mechanism as to how these porphyrins protect normal tissues from radiation damage still remains largely unknown. In the current study, we determine the effects of the manganese porphyrin, Mn...

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Detalles Bibliográficos
Autores principales: Kosmacek, Elizabeth A., Chatterjee, Arpita, Tong, Qiang, Lin, Chi, Oberley, Rebecca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085174/
https://www.ncbi.nlm.nih.gov/pubmed/27119354
http://dx.doi.org/10.18632/oncotarget.8923