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A role for multiple chimeric antigen receptor-expressing leukocytes in antigen-specific responses to cancer

While adoptive immunotherapy using chimeric antigen receptor (CAR)-modified T cells can induce remission of some tumors, the role of other CAR-modified leukocytes is not well characterized. In this study, we characterize the function of leukocytes including natural killer (NK) cells, macrophages and...

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Detalles Bibliográficos
Autores principales: Yong, Carmen S.M., John, Liza B., Devaud, Christel, Prince, Miles H., Johnstone, Ricky W., Trapani, Joseph A., Darcy, Phillip K., Kershaw, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085178/
https://www.ncbi.nlm.nih.gov/pubmed/27153556
http://dx.doi.org/10.18632/oncotarget.9149