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Synonymous mutations in oncogenesis and apoptosis versus survival unveiled by network modeling
Synonymous mutations, which do not alter the encoded amino acid, have been routinely assumed to be ‘neutral’ and would have no effect on phenotype or fitness. Yet increasing observations have emerged to overturn this conventional concept. However, convicted elucidation of how synonymous mutations ex...
Autores principales: | Li, Xiang, Chen, Yuan, Qi, Hong, Liu, Liyu, Shuai, Jianwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085179/ https://www.ncbi.nlm.nih.gov/pubmed/27129147 http://dx.doi.org/10.18632/oncotarget.8963 |
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