FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression

Chemoresistance is common in patients with biliary tract cancer (BTC) including gallbladder cancer (GBC) and cholangiocarcinoma (CC). Therefore, it is necessary to identify effective chemotherapeutic agents for BTC. In the present study, we for the first time tested the effect of farnesoid X recepto...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zhan, Ming, Li, Qi, Chen, Wei, Chu, Huiling, Huang, Qihong, Hou, Zhaoyuan, Man, Mohan, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085180/
https://www.ncbi.nlm.nih.gov/pubmed/27127878
http://dx.doi.org/10.18632/oncotarget.8964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085180/
https://www.ncbi.nlm.nih.gov/pubmed/27127878
http://dx.doi.org/10.18632/oncotarget.8964

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