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Assessment of epigenetic alterations in early colorectal lesions containing BRAF mutations

To clarify the molecular and clinicopathological characteristics of colorectal serrated lesions, we assessed the DNA methylation of cancer-associated genes in a cohort of BRAF-mutant precancerous lesions from 94 individuals. We then compared those results with the lesions' clinicopathological f...

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Detalles Bibliográficos
Autores principales: Sawada, Takeshi, Yamamoto, Eiichiro, Yamano, Hiro-o, Nojima, Masanori, Harada, Taku, Maruyama, Reo, Ashida, Masami, Aoki, Hironori, Matsushita, Hiro-o, Yoshikawa, Kenjiro, Harada, Eiji, Tanaka, Yoshihito, Wakita, Shigenori, Niinuma, Takeshi, Kai, Masahiro, Eizuka, Makoto, Sugai, Tamotsu, Suzuki, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085213/
https://www.ncbi.nlm.nih.gov/pubmed/27145369
http://dx.doi.org/10.18632/oncotarget.9044