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JNK2 downregulation promotes tumorigenesis and chemoresistance by decreasing p53 stability in bladder cancer

Bladder cancer is one of the most common malignancies of the urinary system, and the 5-year survival rate remains low. A comprehensive understanding of the carcinogenesis and progression of bladder cancer is urgently needed to advance treatment. c-Jun N-terminal kinase-2 (JNK2) exhibits both tumor p...

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Detalles Bibliográficos
Autores principales: Pan, Chun-Wu, Liu, Hailong, Zhao, Yu, Qian, Chenchen, Wang, Liguo, Qi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085214/
https://www.ncbi.nlm.nih.gov/pubmed/27147566
http://dx.doi.org/10.18632/oncotarget.9046