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Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression

Metabolic reprogramming is a hallmark of cancer. Elevated glycolysis in cancer cells switches the cellular metabolic flux to produce more biological building blocks, thereby sustaining rapid proliferation. Recently, new evidence has emerged that metabolic dysregulation may occur at early-stages of n...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Chi, Zhang, Chenyu, Zhang, Qingling, Sahin, Ozgur, Wang, Hai, Xu, Jia, Xiao, Yi, Zhang, Jian, Rehman, Sumaiyah K., Li, Ping, Hung, Mien-Chie, Behbod, Fariba, Yu, Dihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085227/
https://www.ncbi.nlm.nih.gov/pubmed/27150057
http://dx.doi.org/10.18632/oncotarget.9136